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It’s time to get engaged!

We’re here to make clinical trials clear and accessible for you. We provide straightforward information so you can make confident healthcare decisions, while helping researchers develop treatments that work for everyone.

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What you need to know

Thinking about joining a clinical trial? Each study has specific eligibility guidelines to ensure your safety and the quality of the research. We’ll help you understand if a particular study might be right for you. These criteria help ensure participant safety and the validity of clinical trial outcomes. Whether you’re looking for paid clinical trials or interested in contributing to medical research, it’s important to understand all aspects of the trial before making a decision.
participants (952,789) took part in clinical research in 2022/23 across England, an increase of over 220,000 on pre-pandemic levels (1)
~ 0
is the average drop out rate across Phase I-III
0 %
clinic trials have been conducted since 2000
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01

What Are Clinical Trials?

Did you know it can take anywhere from 10 to 15 years to develop a new medicine? It’s a long journey, and clinical trials are a key part of that drug development process!

These medical trials are research studies where scientists, doctors, nurses, and healthcare professionals test new ways to treat illnesses. Clinical trials help us learn if a new experimental treatment is safe and if it works.

Who Can Participate?

Clinical trials need people like you. Whether you’re living with a health condition or are completely healthy, your participation matters.

Researchers welcome people of all ages, from young children to older adults. They need both healthy volunteers and patient volunteers with different backgrounds and lifestyles. And they need people with a variety of health conditions, not just those who are healthy. Why such a wide range of people? Because this helps researchers learn how new treatments might work for different groups of people. It’s how they make sure new medicines are safe and effective for everyone.

02

What Are the Phases of a Clinical Trial?

Clinical trials have different stages, also known as clinical trial phases. Each stage in these clinical trial stages has a different number of people participating:

Safety First – A small group of 20-80 volunteers helps researchers understand how the body responds to a new treatment and what side effects might occur. These pioneering participants play a crucial role in determining if a treatment is safe to study further.

After establishing safety, researchers work with 100-300 people who have the condition being studied. This phase explores whether the treatment shows promise in addressing the illness and continues to monitor safety.

Now researchers give the medicine to an even bigger group, often hundreds or even thousands of people. Doctors compare the new medicine to older medicines or a placebo to see which one works best. This phase often involves randomisation to ensure unbiased results.

Even after a medicine is available for everyone to use, doctors continue to study it in large groups of people to make sure it’s safe and working well.

03

What to Expect When you Join a Clinical Trial

We understand that volunteering to participate in research is a big decision. This information will help you understand what to expect during participant recruitment and throughout the study.
  • Dedicated healthcare team: As a participant, you’ll receive attentive care from medical professionals who closely monitor your health throughout the study. Many participants value this personalized attention as one aspect of their trial experience.

  • Early access to new treatments: You might get to try a new medicine that could help you feel better, even before it’s available to everyone else. This might be something that could really improve your health, especially if you are not on any treatment or if the medicine or treatment you are on now isn’t working well or at all.
  • Help others: By joining a clinical trial, you’re not just helping yourself. You’re also helping doctors learn more about illnesses and how to treat them, which could help lots of people in the future.
  • Potential Side effects: Every treatment being studied may cause side effects, ranging from mild to serious. Before you join, the research team will discuss specific risks for the particular study and what they’re doing to minimise them. Your safety remains the top priority throughout the process.

  • The treatment may not work: There’s no guarantee that a new treatment will be effective. Even if it shows promise, it might not work for everyone.

  • Time commitment: Clinical trials can require a significant time commitment, with regular visits to the clinic or hospital for tests and checkups.

04

What Are the Potential Benefits and Risks?

Participating in a clinical trial can offer potential benefits to individuals, such as access to new treatments and close medical monitoring. However, it’s important to recognise that every research study has potential risks and that individual experiences may vary.

  • Dedicated healthcare team: As a participant, you’ll receive attentive care from medical professionals who closely monitor your health throughout the study. Many participants value this personalized attention as one aspect of their trial experience.
  • Early access to new treatments: You might get to try a new medicine that could help you feel better, even before it’s available to everyone else. This might be something that could really improve your health, especially if you are not on any treatment or if the medicine or treatment you are on now isn’t working well or at all.
  • Help others: By joining a clinical trial, you’re not just helping yourself. You’re also helping doctors learn more about illnesses and how to treat them, which could help lots of people in the future.
  • Potential Side effects: Every treatment being studied may cause side effects, ranging from mild to serious. Before you join, the research team will discuss specific risks for the particular study and what they’re doing to minimise them. Your safety remains the top priority throughout the process.
  • The treatment may not work: There’s no guarantee that a new treatment will be effective. Even if it shows promise, it might not work for everyone.
  • Time commitment: Clinical trials can require a significant time commitment, with regular visits to the clinic or hospital for tests and checkups.

05

Your Rights as a Participant

 

  • Informed consent: You have the right to receive clear and complete information about the trial before you decide whether (or not) to participate. This process ensures you understand the study protocol, potential risks, and benefits.

  • Withdrawal: You have the right to withdraw from the trial at any time, for any reason, without penalty.

  • Confidentiality: Researchers will keep your personal information and medical records confidential.

Everyone deserves a voice in shaping the future of healthcare. pRxEngage is expanding access and improving clinical trials through patient empowerment. 

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